Any discussion of a Biden administration strategy on Iran must begin with an analysis of how previous U.S. administrations have approached the threat posed by Iran. From the very start of the Islamic Republic forty-one years ago, U.S.-Iran relations have been fraught with mistrust, animosity, threats, and occasional active hostilities, but interspersed with periods of negotiation and even tacit cooperation in selected circumstances. Yet, none of the Iran strategies pursued by seven U.S. administrations since the Islamic Revolution in 1979 has succeeded in neutralizing the wide range of threats Iran still poses to U.S. interests and allies.